Lipophilicity and biomimetic properties in drug discovery
The course is designed for medicinal chemists, analytical chemists working in early drug discovery. You will learn how lipophilicity and biomimetic properties influence in vivo drug distribution.
Short introduction to lipophilicity and biomimetic properties in drug discovery
The course includes eight 3-min video introduction to lipophilicity and how to measure biomimetic properties using chromatography. At the end there is a quiz to test your knowledge so that you can go to the next level.
Solubility and permeability
You will learn the definitions of solubility and permeability, how to measure these parameters at early drug discovery and how to use the data to estimate intestinal absorption.
Lipophilicity and biomimetic properties supporting early drug discovery
This course is part of the Drug Discovery and Pharma Management master course at UCL School of Pharmacy
Modeling in vivo distribution of drugs
This course describes the estimation of in vivo drug distribution based on biomimetic properties. Volume of distribution, unbound volume of distribution, drug efficiency brain to plasma ratio.