Modeling in vivo distribution of drugs
course describes how to estimate volume of distribution, drug efficiency and various tissue binding from measured biomimetic properties.
This course describes the estimation of in vivo drug distribution based on biomimetic properties. Volume of distribution, unbound volume of distribution, drug efficiency brain to plasma ratio.
Klara Valko
Background
How to use this course
Handout for volume of distribution
Volume of distribution
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Handout for unbound volume of distribution
Modelling unbound volume of distribution
Summary of volume of distribution and unbound volume of distribution
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Handout for drug efficiency
Drug efficiency and drug efficiency index
Summary of drug efficiency
Summary of drug efficiency index
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Plasma and tissue binding handout
Plasma and tissue binding models
Video 10.2 Plasma and tissue binding models
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Here is the possibility to ask questions from the tutor